The structure method introduced by Pritchard et al. in 2000 has quickly become one of the most widely-used analytical methods in population genetics and phylogeography (more than 1,000 citations in seven years!). It's popularity is sure to grow as extensions are developed and the type of multi-locus genetic data it requires accumulates for non-model organisms. With the release of a cross-platform graphical front-end in 2007, users who were scared of by its somewhat cumbersome command-line interface are out of excuses. Although veteran users may prefer to stick with the command line interface, I've found the graphical front-end to be a helpful supplement. It's particularly useful for visualizing the results of structure analyses, including generation of the iconic structure diagrams that previously required Noah Rosenberg's complementary distruct package. Don't trash your copy of distruct just yet though, you're still going to need it to produce high quality images for publication; the structure GUI produces low quality JPG images and has limited options for custom labeling. OK, now go play!
If you need support for structure, you should consult it's outstanding user manual (it's included as the readme.pdf file in the doc folder of a standard structure installation), or the wonderful tutorial that Bob Thompson posted over at the Bodega Phylogenetics Wiki. I just added a foot-note to Bob's tutorial that you might find helpful for installation of the front-end on Mac OSX machines if you have little or no experience navigating UNIX file architecture.
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